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Hyperpigmentation is a medical condition, and every treatment described here is prescribed and administered by a licensed provider after an in person evaluation

As a result, levels of free leptin were higher in the GLP-1RA group, which may counteract the weight-preserving actions of the physiological leptin decrease during weight loss maintenance as smaller decreases in levels of free leptin would be expected to prevent the leptin-mediated appetite increase and energy expenditure decrease that normally occurs in response to weight loss

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