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Steroids and peptides are different molecules and are subject to different regulations

Abstract Animals rely on nervous systems to cope with environmental variability, whereas plants are characterized by lack of nervous system but still have evolved systemic communication systems through signaling molecules that trigger long-distance defense signaling events when encountered with environmental challenges

Daily supplementation may need to be continued, but cobalamin blood levels could be monitored with less frequent dosing to see if decreased frequency of administration is adequate

As clinicians, rational prescribing is our responsibility ensuring benefit while minimizing harm