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In addition, as seen in Dpp4 / mice, basal levels of HGP were unchanged, and Dpp4 hep/ mice showed lower HGP under clamp conditions and greater insulin suppression of HGP (Figure 1, I and J)

GLP-1/GIP analogues: Potential impact in the landscape of obesity pharmacotherapy

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Studies were conducted with permission from the Danish Animal Experiments Inspectorate (2023-15-0201-01408) and the local ethical committee (EMED P23-262 and P23-263) in accordance with the EU Directive 2010/63/EU and guidelines of Danish legislation governing animal experimentation (1987) and the National Institute of Health