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similarly, in the pulmonary circulation, endothelial dysfunction has been identified as an early event leading to the development of pulmonary hypertension in the context of experimental heart failure [21]

Beyond metformin: safety considerations in the decision-making process for selecting a second medication for type 2 diabetes management: reflections from a diabetes care editors' expert forum

Biomed Pharmacother 111:841851 El-Akabawy G, El-Sherif NM (2019) Zeaxanthin exerts protective effects on acetic acid-induced colitis in rats via modulation of pro-inflammatory cytokines and oxidative stress

Abstract Aims/hypothesis A protective role of sodiumglucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP1-ra) in the development of diabetic retinopathy and diabetic macular oedema has been described in some recent studies, which may extend beyond glycaemic control