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The first feature is hyperandrogenism, which can be assessed biochemically by elevated testosterone levels and increased dehydroepiandrosterone sulfate (DHEAS) or androstenedione (ANSD) [44]

For targeted therapeutic support during severe symptom flares or intense detoxification protocols, some functional medicine providers may recommend temporarily increasing the dose to 300 mg or 400 mg per day, though this should always be done under medical supervision

Similar outcomes were observed by Behairy et al