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Here, we provide a concise overview of the core physiology of GLP-1 secretion and action, and the role of the peptide in human health, disease and therapeutics
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Ht31, a protein kinase A anchoring inhibitor, induces robust cholesterol efflux and reverses macrophage foam cell formation through ATP-binding cassette transporter A1
Endoplasmic reticulum stress and oxidative stress The accumulation of lipotoxic speciesincluding free fatty acids (FFAs), diacylglycerols, phospholipids, and free cholesteroltriggers endoplasmic reticulum (ER) stress, leading to activation of multiple cellular stress pathways
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