They explain in an editorial for the South African Medical Journal that evidence shows, on their own, recommendations for diet and exercise are unable to combat obesity and contribute to societal stigma and individual shame
Compounding pharmacies make customized medicines for individual patients, and under section 503A of the Food, Drug, and Cosmetic Act, a pharmacy can compound from a bulk substance only if that substance has an official quality monograph, is a component of an FDA-approved drug, or has been formally added to an approved bulks list. BPC-157 qualifies on none of those counts, which is why the FDA placed it in Category 2 of its 503A bulk-substance review in September of 2023
The primary outcome was a composite of the need for oral corticosteroids, tumour necrosis factor- inhibitors, IBD-related hospitalisation, or IBD-related surgery
Additionally, cytokine-targeting therapies, including tocilizumab (an anti-IL-6 receptor inhibitor) and anakinra (an anti-IL-1 receptor antagonist), have been shown to be effective in treating immune-mediated epileptic syndromes, such as new-onset refractory status epilepticus (NORSE) and febrile infection-related epilepsy syndrome (FIRES) [358, 359]
