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Many patients taking GLP-1 receptor agonists for diabetes or weight management report improvements in joint pain, prompting questions about whether these medications directly address musculoskeletal symptoms

As GH is secreted in the body, it prompts the release of IGF-1 from the liver, which in turn regulates the growth effect throughout the body

4 A separate 2025 retrospective study of over 450,000 matched patients found that semaglutide specifically was associated with the strongest protective effect among GLP-1 receptor agonists, with a 32% reduction in epilepsy risk

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