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A closer look at how weight loss drug semaglutide improves the cardiovascular health of obese patients without diabetes Weekly treatments of semaglutide can reduce the risk of cardiovascular death, heart attack or stroke among obese patients without diabetes, according to new data presented at the American Heart Associations Scientific Sessions 2023 conference and simultaneously published in The New England Journal of Medicine .[1] Subcutaneous treatments of semaglutide, a GLP-1 receptor agonist originally developed to treat diabetes, are being sold and marketed by Novo Nordisk under the brand name Wegovy