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Laura Dawes: And those kinds of dramatic changes really made endocrinology and endocrinologists super excited about the possibilities for their field

Before propensity score matching, the semaglutide group included 127, 352, and 498 patients across the three BMI subgroups, respectively, while the control group included 11,277, 8,722, and 6,870 patients

Wegovy (semaglutide for weight loss) carries an indication for adults and children aged 12 and older, making it technically available for some adolescentsbut only under strict medical criteria and physician oversight

Panel b : The proportion of participants achieving total body fat mass reduction thresholds at Week 72 is calculated based on logistic regression with mixed model repeated measures for missing data imputation using an efficacy estimand