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These practices may be due to medical providers having biases about which patients will be able to afford certain medications, or about the effectiveness of medications in different patient groups. Rocio Pereira, MD, chief of Endocrinology, Denver Health
In addition, 1,25(OH)2D3 induces the release of neurotrophin and synthesis of Ca 2+ -binding proteins such as parvalbumin, inhibits the synthesis of inducible iNOS, macrophage colony-stimulating factor, TNF-, down-regulates L-type voltage sensitive Ca 2+ channel (LVSCC), and upregulates -glutamyl transpeptidase activity, which are also reported to be the potential neuroprotective mechanisms of VD in PD (Figure 2A) (9193)