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When levels are low, patients may experience fatigue, brain fog, or mood changes

DMF has been shown to suppress the proinflammatory condition of SCD in animal models 25 , suggesting its therapeutic potential for individuals with SCD

Many of the studies reviewed highlight promising behavioral, neurochemical, or microbiota-related effects of probiotic and prebiotic interventions, yet very few include direct measurements of oxidative-stress biomarkers

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