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Challenges and Perspectives GLP-1 receptor agonists look really promising for treating neurological disorders, but there are several obstacles that need to be overcome before they can be widely used

Lilly said recently that sales of Zepbound have tripled so far this year to more than $9 billion

Most of the added risk came from a temporary, usually reversible type of shedding linked to rapid weight loss and reduced calorie intake, not permanent damage to hair follicles

Weight-loss medications in the 20th century proved to be equally dangerous: dinitrophenol, a mitochondrial proton pump uncoupler, was remarkably effective at shedding pounds but led to nerve malfunction and arrhythmia induced fatalities