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In pharma, innovation is not always about discovering a new drug

Transcranial Doppler pulsatility index is not a reliable indicator of intracranial pressure in children with severe traumatic brain injury

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A small observational study (2023) in the journal *Obesity* suggested additive weight loss in a cohort of 47 patients on both agents, but sample size, lack of randomization, and absence of long-term follow-up prevent firm conclusions