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Mechanism and Factors Involved: Because of the many physical and chemical manipulations required in upstream production and downstream processing, followed by formulation and filling operations, aggregation of protein biopharmaceuticals can be induced during nearly every step of the process including at hold points, shipping, and long-term storage (16,21)

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After reconstitution: Keep refrigerated at 28 C and use within 30 days

Instead of forcing insulin out all the time, GLP-1s enhance the bodys natural, glucose-dependent insulin response, meaning insulin is released primarily when blood sugar is elevated