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Impaired or incorrect activities of glutathione peroxidase (GPx), catalase, superoxide dismutase (SOD), and antioxidative compounds in the blood and decreases in the antioxidative capacity of the above-listed markers are frequently detected in ASD [36,37]

However, in female livers increased 1, 1i and 5i expression, as well as a trend towards the increase in proteasome activities (2, 1i, 5i) and 2i expression, suggest that ibuprofen activated a compensated stress response in female livers as a mechanism to adapt to various stressors

Many researchers in the field of toxicology and liver disease have suggested that supplementation of glutathione (GSH) could be particularly useful

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