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Different populations of human locus ceruleus neurons contain heavy metals or hyperphosphorylated tau: implications for amyloid- and tau pathology in Alzheimers disease

The pathways that transduce GLP-1RAmediated reduction of BP are not well defined, and kidney-centric mechanisms such as inhibition of tubular salt reabsorption, vascular inflammatory immune cell infiltration, central regulation of vascular tone, and either EC- or VSMC-regulated vasodilation have been proposed (33)

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