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Neither compound has published the kind of long-term hard-outcome data (cardiovascular events, mortality) that ultimately defines a metabolic drugs value, because both are too early in development for that

Short-term side effects were not observed in this small population, and they did not evaluate if it actually worked for a specific condition or if it was safe for long-term use. Jamie Richardson, BVetMed, head of veterinary medicine at Small Door Veterinary, shares the same concerns

In summary, the molecular mechanisms associated with obesity and IR play a pivotal role in the development of the SLCI in PCOS (140)

The effect of these peptides is real but modest