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Weight loss is usually observed within the first 12 weeks of Tirzepatide treatment, and continued weight loss may be seen with longer-term use

No induction of an inflammatory response as measured by IL-8 release in the ALI cultures was observed

In the central nervous system (CNS), during embryogenesis and adulthood, efferocytosis by ramified microglia balances cell death and neurogenesis, ultimately supporting brain development, optimizing neuronal connectivity, and ensuring that inflammatory responses remain appropriate and effective [25, 26]

As the false lumen expands, it can lead to severe complications such as aortic valve insufficiency, pericardial tamponade, or even rupture of the aorta