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Indirectly, ROS clearance is facilitated through the inhibition of the NF-B pathway, which consequently downregulates the expression of inflammatory mediators and cytokines, such as tumor necrosis factor-alpha (TNF-) and interleukin-8 (IL-8)

Moreover, it had been seen that a 100% encapsulation efficiency with a high stability was achieved when idarubicin, daunorubicin and doxorubicin were loaded in drug/lipid ratio of 0.3 w/w [150]

A novel PEGylated carbon nanotube conjugated mangiferin: An explorative nanomedicine for brain cancer cells