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Abstract Over a relatively short period, obesity and type 2 diabetes have come to represent a large medical and economic burden to global societies

Jan 8, 2026 Fibromyalgia represents a central sensitization disorder where the nervous system amplifies pain signals, creating widespread discomfort from stimuli that would not normally register as painful

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Retatrutide simultaneously targets GLP-1, GIP, and glucagon receptors, making it distinct from approved agents such as semaglutide (Wegovy) and tirzepatide (Mounjaro)