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"At least 50% price cuts from current (semaglutide price) levels is something the generics companies may start with depending on how many players are in the market in the first wave," said Vishal Manchanda, pharma analyst at broking firm Systematix Group

Beyond CagriSema, researchers are exploring GLP-1 combined with FGF21 analogues, GLP-1 combined with leptin sensitizers, and even triple or quadruple receptor agonists

Participants were randomized 1:1:1 to retatrutide 9 mg weekly, retatrutide 12 mg weekly, or placebo, with treatment lasting 68 weeks

Nearly all public and private insurance plans cover Ozempic for Type 2 diabetes