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Stage II trial (NCT06564753) Design: A 13 week randomized, double-blind, placebo-controlled study included 125 obese (BMI 30kg/m ) or overweight (BMI 27kg/m with concomitant metabolic disorders) participants

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The trial was designed to assess the efficacy and safety of semaglutide, a once-weekly subcutaneous glucagon-like peptide 1 (GLP-1) receptor agonist, in preventing major kidney outcomes, specifically kidney failure, substantial loss of kidney function, and death from kidney or cardiovascular causes, in individuals with type 2 diabetes and chronic kidney disease

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