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Current evidence Although B12 supplements are commonly taken to boost energy levels, there is currently no evidence that higher B12 levels increase energy in people with adequate B12 levels

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Similarly, single doses of 60 mg, 120 mg, and 180 mg taken one hour before oral glucose tolerance testing effectively improved fasting blood glucose levels as well as glucose and insulin responses in pre-diabetic individuals, with 180 mg having the greatest impact on blood glucose levels (Alvarado, Leschot 2016)