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Specifically, Retatrutide is a triple agonist that targets three key receptors-GLP-1, GIP, and glucagon-working together to suppress appetite, increase fat burning, and boost energy expenditure

Early animal research is promising AOD-9604 injected into arthritic joints enhanced cartilage regeneration, especially when combined with hyaluronic acid

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In the Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes published in 2024, it was recommended to start GLP-1 RA sodium-glucose co-transporter 2 inhibitors (SGLT2i) in patients with T2DM and ASCVD, while also commenting upon noted benefit in specifically HFpEF as well [53]