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This study shows that when smokers interested in reduction are provided with an e-cigarette that has cigarette-like nicotine delivery, they are more likely to achieve significant decreases in tobacco-related toxicants, such as lower exhaled carbon monoxide levels. The researchers conducted a randomized controlled trial of 520 participants who smoked more than nine cigarettes a day, were not currently using an e-cigarette device, and were interested in reducing smoking but not quitting

The harmful chemicals in the smoke can penetrate the hair shaft, leading to damage and weakening of the hair

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Although the precise mechanisms linking this to lung inflammation have not been fully elucidated, the likelihood that this may be involved in lung diseases is suggested by the vast and growing evidence for the role of mtDNA in sterile inflammatory conditions (Riley and Tait, 2020