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As roadways improved, Richmond, with its river and rail access, became the locus of the tobacco trade, and has remained so ever since
Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Register cohorts
10% market share, which still paled in comparison to British American Tobacco that held a staggering 55% share of the market
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