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We searched three databases, PubMed, Global Index Medicus, and Web of Science, from January 1, 1970, through January 30, 2023, regardless of language of publication

doi:10.1016/j.addbeh.2021.106917

The remaining 111 publications, which report on 103 studies, use prospective cohort, retrospective cohort, or case-control study designs and provide data on the association between the outcome of interest and chewing tobacco broadly, or specific chewed forms of tobacco, among a general population

The study also found that the heart rate was at its peak in all four categories within the first 30 minutes of use, both heart rate and blood pressure were almost back too normal by the end of the session in all categories.I do not believe that smokeless tobacco can cure your smoking addiction although it has a lower nicotine input