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The authors hoped to test four hypotheses: That an excess of tobacco use is already present in people presenting with their first episode of psychosis That daily tobacco use is associated with an increased risk of subsequent psychotic disorder That daily tobacco use is associated with an earlier age at onset of psychotic illness That an earlier age at initiation of smoking is associated with an increased risk of psychotic disorder The authors followed MOOSE and PRISMA guidelines for the conduct and reporting of systematic reviews and meta-analyses, and searched Embase, Medline and PsycINFO for relevant studies

doi:10.1001/jama.2013.284427

In the present study, animals exposed to TFC smoke (without tobacco) presented anxiety-related behaviour in the elevated T-maze

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