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While not much is known about the long-term risks, and though closed systems appear to be less risky than open systems, the best advice may be to educate adolescents on the risks of both systems and encourage them not to pick up the habit in the first place

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Discussion We identified 12 relevant studies examining the association between EC use and subsequent respiratory outcomes among PWNS

While there are no significant health risks when quitting smoking cold turkey, nicotine withdrawal symptoms can be very unpleasant