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After all, the receptor it binds to in the brains neuronsa type of acetylcholine receptor, which also binds the neurotransmitter acetylcholineis found in large numbers in muscle cells

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All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases [see Boxed Warning]