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In 2009, Cohen et al., also reported on the exposure of epithelia cell cultures to the particulate phase of cigarette smoke reducing cilliary beat increase when stimulated.13 Besides in vitro evidence, the exposure to cigarette smoke also harms mucociliary transport in humans, both in acute exposure14 as well as in its chronic counterpart.15,16 Cigarette smoking is also associated with profound changes in mucous production mechanisms

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Other investors in Japan Tobacco include Mizuho Trust & Banking, Goldman Sachs and the Childrens Investment Fund Management

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