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Because fluoroquinolones, including CIPRO, have been associated with serious adverse reactions [see Warnings and Precautions (5.15.16)] and for some patients AECB is self-limiting, reserve CIPRO for treatment of AECB in patients who have no alternative treatment options

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Additionally, in vitro , upregulated NEAT1 expression was positively correlated with the mitochondria damage of the lung epithelial cells and with the increased expression of PINK1