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This is why they must deliver nicotine in a way that is competitive with a cigarette, the most effective nicotine delivery system created to date," Nicotine Content Comparison (What goes into the product): More Than Just Milligrams The amount of nicotine is one of many factors determining uptake Nicotine uptake is determined by several factors including nicotine content, product format , pH , moisture levels and individual differences

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adults, particularly among populations with the highest rates of use, the CDC said

Blending : Different tobacco leaves might be mixed to create a particular blend