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While cigarette smoke-induced inflammation is meant to serve as a natural/protective response, it may make children more vulnerable to illness, since the inflammatory mediators associated with CSE may result in exacerbation of inflammatory and remodeling pathways typical of chronic pediatric lung disease

Therefore, the realised prevalence scenario has more of both never smokers and former smokers, compared with the constant prevalence scenario

D2-like receptors and G-protein coupling in the ventral striatum was also enhanced in combination with altered roles of D2 and D3 receptors in cocaine-induced behaviors

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