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Collectively, these findings underscore that cigarette smoking is not only associated with an increased risk of developing PBC but also accelerates disease progression, worsens fibrosis, elevates HCC risk, and contributes to poorer long-term outcomes

Sepaniak S, Forges T, Gerard H, Foliguet B, Bene MC, Monnier-Barbarino P

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At the first muffled roar and crackling sound of rendered timber, all hands except the enfilading pairfrom the city editor to the meekest copy boywould secure shotguns conveniently placed for the purpose and rush to the front windows looking out on the street below, knowing full well that the miscreant Hennessy must, perforce, make egress and briefly present a target