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al, J Chem Phys 110, 5403-5411, 1999) The relaxivity values are not only related to the iron content but also to the size of the nanoparticles PEGylated nanoparticles (whose surface is modified by PEG or polyethylene glycol ) have lower relaxivities, but r2 equal to or slightly greater than those of non-PEGylated materials PEG coating can modify relaxivities according to two opposite effects: on the one hand, it increases particle size, on the other hand it decreases their ability to aggregate

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