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Due to the fact that nicotine has been reported to influence mitochondrial function both in vitro and in vivo and the precise mechanisms underlying the effects of nicotine on mitochondrial function remain largely unknown, this review will focus on the primary action of nicotine on mitochondrial physiology at the cellular and organism level

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Tobacco use continues to be one of Canadas most significant public health problems, and is the countrys leading preventable cause of disease and premature death, said Minister of Health Jean-Yves Duclos