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In a 2005 study published by the Scandinavian Journal of Gastroenterology, researchers found that 2mg nicotine pouches showed no significant impact on rectal tone
The study also supports their effectiveness when compared to other methods of quitting, including nicotine replacement therapy or medication
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These habits may affect the activity of the mitochondrial respiratory chain as well as the replication and transcriptional regulation of mitochondrial genes, leading to altered mitochondrial function and, in turn, to psychiatric disorders 59
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