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For the tobacco industry, the larval feeding on tobacco (especially flue-cured and oriental) is the most significant damage

Theres an ever so slight fruity twang to Bravura present that complements the earthiness of the juice perfectly

In answer to the more direct question of how much nicotine per day is safe, a reasonable starting point might be, "How much nicotine might it take to poison someone?" The ECHA currently gives an "acute toxicity estimate" (ATE) for nicotine via the oral route to be 5 mg/kg bw [7] , meaning 5mg of nicotine for every kilogram of bodyweight of the person consuming the nicotine