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Compared to traditional cigarettes, the vapour generated by Juul contains almost 100% less carbon monoxide and carbonyl compounds like acetaldehyde, formaldehyde, and acrolein (a major irritant in cigarette smoke) (Table 1)

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Dr Haaker and his colleagues at the Karolinska Institute in Stockholm, Sweden and the Johannes Gutenberg University Medical Centre in Mainz, Germany, examined the fear responses in 376 healthy volunteers, a fifth of whom were regular smokers