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This imbalance in the lung microbiome may disrupt immune homeostasis and contribute to inflammation, suggesting potential therapeutic targets such as probiotics (Fig

The risk is even higher for those who use smokeless tobacco, such as chewing tobacco or snuff, which directly contacts the soft tissues in the mouth for prolonged periods

Nationally, smoking prevalence among high school students was 3.8%.2 Other tobacco product use: Pennsylvania* Vaping rate in Pennsylvania In 2022, 7.4% of adults in Pennsylvania used e-cigarettes.3 Nationally, adult e-cigarette use prevalence was 7.7%.1 In 2022, 4.8% of adults in Pennsylvania used smokeless tobacco every day or some days.1 Nationally, adult smokeless tobacco use prevalence was 3.4%.1 In 2021, 19.2% of high school students in Pennsylvania used electronic vapor products on at least one day in the past 30 days

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