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The mixed effects model for the analysis of PK parameters (AUC and C max ) was specified as follows:where, observed [e.g., ln (AUC or C max )] overall mean effect of the i th investigational product, a fixed effect effect of the j th sequence, a fixed effect effect of the k th period, fixed effect effect of the p th subject nested within the j th sequence, assumed i

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Devers is already one of the game's best hitters at age 25 and is in the midst of a career year with a .324 batting average, an American League-leading 122 hits, 22 home runs and 55 RBIs through 86 games