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BMJ (Clinical research ed) 2007;335(7609):20

ESCALATING YOUTH E-CIGARETTE USE In just one year, from 2017-2018, e-cigarette use among high schoolers increased an incredible 78%, the largest single year increase in the use of any substance by youth in the more than 40- year history of the National Institutes of Health-sponsored survey that collected these data

Once cancer cells enter the bloodstream, they can travel to any region of the body (metastasis)

But they are regulated by the states Department of Consumer Protection, which regulates tobacco products and smoking cessation products such as nicotine gum and patches