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While the precise mechanisms by which smoking increases cardiovascular disease are still being discovered, it has been shown to exert direct myocardial effects, such as increasing myocardial oxygen demand, lowering the threshold for angina, and Impairing exercise performance (Figure 2)

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Im sorry for the error Reply Pat LaFleur on August 11, 2023 at 8:44 am Dr Kandaria Im 69 yrs old I have had a lower face and neck lift co2 laser treatment and the deep smoker lines have returned I was told that the retinol really wont work on such deep lines Ive tried filler and to me all it did was make me look like a duck Help whats next Reply Dr