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This review discussed the significant effect that E-cig use had on the BC tumor microenvironment, which ultimately led to enhanced tumor malignancy and metastasis, with an emphasis on the extent that E-cig uses had on the crosstalk between cancer and immune cells, as well as the potential underlying mechanisms that drive this aggressive phenotype of BC

Nicotine patches are transdermal patches that release a steady, controlled amount of nicotine into the bloodstream through the skin

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Conversely, no differences in lung function or histopathological changes were observed following exposure to e-cigarette aerosol, and less lung inflammation was observed in Apoe-/- mice [34, 35]