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Toxic mechanism Nicotine binds stereoselectively to nicotinic acetylcholine receptors (nAchRs), which are pentameric ligand-gated ion channels (LGICs), localised in the peripheral and central nervous system, autonomic ganglia, sympathetic and parasympathetic nervous system, and skeletal neuromuscular junctions 10 , 23

The report is segmented by Product (Modular e-cigarette, Next-generation products, Rechargeable e-cigarette, and Disposable e-cigarette), Distribution Channel (Offline, and Online), Type (Open, and Closed), Product Type (Automatic e-cigarette, and Manual e-cigarette) and Geography (North America, Europe, APAC, South America, Middle East and Africa) Which regions are analyzed in the report