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The positive association between e-cigarette use and the 2635 age group, in contrast to the 1820 age group, aligns with global trends

Since screening toxicological studies are costly and time consuming, the huge heterogeneity of vape products and the significant amount of monthly released new products prevent an exhaustive assessment

However, this finding also accords with internal tobacco company documents describing small packages as offering a low cost way for current users to try and potentially switch to new brands, particularly in markets with rising prices and among people who are younger and poorer [20]