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The federal government could do more as well, including ensuring the tobacco industry is held accountable for waste they produce and enforcing all guidance and best practices regarding tobacco products waste disposal
To this end, there has been an increasing shift from using the gold standard endpoint of overall survival (OS) (see Sidebar 28 ), to earlier endpoints like progression free survival, overall response rate, and duration of response to achieve an accelerated approval designation from FDA
After reviewing our longstanding policies for the immunosuppressive drug benefit and engaging with interested parties about current practices and challenges, we are proposing policies aimed to reduce barriers faced by beneficiaries receiving immunosuppressive drugs under this benefit, as described below
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