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82 Nicotine is responsible for an increased adhesion of planktonic bacteria to the tooth biofilm and its thickening due to an increase in the synthesis of extracellular polysaccharides (EPS), glucosyltransferase (Gtf) and glucan-binding protein (Gbp) at the mRNA and protein levels

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The main purpose of CBT is to help patients identify triggers and teach them coping mechanisms to resist cravings or prevent relapse